Chromosomal abnormalities and inherited conditions in psychiatry

by Dr Bronagh Sproule and reviewed by Dr William Howie


Learning outcomes:


By the end of this module, you should be able to:


  • demonstrate knowledge and understanding of the aetiology of commonly encountered chromosomal syndromes
  • accurately describe and differentiate between the clinical presentations of commonly encountered chromosomal syndromes
  • identify and describe the genetics and clinical manifestations of single-gene disorders relevant to psychiatry
  • demonstrate understanding of the genetics of trinucleotide repeat disorders, and how they may manifest clinically
  • accurately describe heritability phenomena, including genomic imprinting and genetic heterogeneity
  • demonstrate knowledge and understanding of the concepts of heritability and family concordance as regards psychiatric disorders
  • demonstrate understanding of the genetic contribution to the aetiology of affective disorders and schizophrenia, and to addiction disorders
  • identify and describe the genetic aetiology of Alzheimer’s disease.


Start the module

If you like this module, you may also be interested in:


Basic genetics by Dr Katharine McMillan and Dr Kimberley Kendall


Clinical genetics by Dr Kimberley Kendall 




Related Advances and BJPsych articles


Download take-home notes to print and annotate


Key reading: selected texts to read with this module


Exam syllabus 

© 2020 Royal College of Psychiatrists